“Comment your blood group below” The blood group of a husband and wife typically refers to their ABO blood type (A, B, AB, or O) and Rh factor (positive or negative). While the ABO blood type doesn’t usually affect compatibility in marriage or pregnancy, the Rh factor can be important during pregnancy. If the wife is Rh-negative and the husband is Rh-positive, there is a possibility that the baby might inherit the Rh-positive blood type. This mismatch can lead to a condition called Rh incompatib