A Nature Methods benchmark of 11 segmentation methods across 15 spatial transcriptomics datasets shows that algorithm and ...

An integrated single-cell atlas of more than 375,000 endothelial cells from 12 human tissues identifies conserved ...

Spatial transcriptomics can reveal where thousands of genes are active across a tissue, creating molecular maps at single-cell resolution. But comparing two such maps is difficult: thin slices of ...

Spatial transcriptomics (ST) shows which genes are being expressed and where within a tissue. Spatial metabolomics (SM), on the other hand, maps the location of metabolites—small molecules produced or ...

The developing cortex does something researchers had not previously demonstrated: it deliberately constructs an entire class of inhibitory neurons, wires them into active circuits, and then ...

Adenomyosis is a common gynecological condition characterized by ectopic endometrial-like tissue deep within the myometrium, causing debilitating symptoms. Treatment options are limited to hormones ...

We knew Apple’s Worldwide Developers Conference would be full of AI, but I didn’t expect to see a photo feature that would make me think: “This is wild.” During the WWDC keynote on Monday, Apple ...

Apple introduced a new AI-powered photography tool at WWDC called Spatial Framing. Credit: Apple It was a big day for Apple Intelligence, Apple's distinctly branded suite of AI tools, at the company's ...

Cell atlasing efforts rest on a deceptively simple premise: To understand a tissue, you must find every cell in it, including the rare populations and transitional states whose biology is often the ...

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

This repository contains tutorials on segmentation of frog embryos for MERSCOPE spatial transcriptomics. Two custome Cellpose2 models trained for segmentation of cells from Xenopus.laevis are provided ...

Transcriptomic analysis of the mouse locus coeruleus noradrenergic (LC-NE) system, integrating single-nucleus RNA sequencing (snRNAseq), spatial transcriptomics (MERFISH), and retrograde-labeled ...