Over the past decade, there have been scattered reports of mammalian cells’ own DNA being found in the cytoplasm, mainly in the context of disease and aging. While it is not unusual to find DNA from ...

The segregation of yolk from the surrounding cytoplasm in the very early fish embryo is a key process for the development of the fish larva. Researchers found that actin dynamics in the bulk of the ...

How do cells detect non-self double-stranded DNA (dsDNA) molecules? Several 'sensors' of RNA, including Toll-like receptors (TLRs) and the RNA helicases RIG-I and Mda5, have been shown to be essential ...

In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...

A new study suggests that DNA synthesized in the cell cytoplasm drives retinal cell death in an advanced form of age-related macular degeneration, a leading cause of blindness.

Put a banana in a blender, and you don’t expect to get it back. But blend up a bunch of living cells and new research suggests that you maybe should. If simply left alone, the liquid innards of a cell ...