Adrien Brody and Sarah Polley play Clive and Elsa, brilliant biochemists who have led the way in creating a new organism culled from the DNA of several existing species. This new animal produces ...

When Vincenzo Natali introduced Splice-- his latest film after Nothing, Cyper, and his cult-smash Cube-- tonight at its world premiere, he simply said that this "film has no moral boundaries." Instead ...

Above all, Elsa does not want to give up and quickly dispels Clive's initial concerns. In secret, the couple embark on the ultimate experiment: creating a human-animal hybrid. The experiment succeeds; ...

The scientists at the center of Splice should have watched a couple of horror movies - that way, they'd know to never go against the moral code and inject human DNA into one of their genetic creations ...

For all the jolts, gore and horror, a scary movie is all about mood. If the tone is off even a notch, an audience will laugh, instead of scream, or roll their eyes, rather than shut them. “Splice” is ...

Steeped in geek-dom and centered with science fiction, Splice is a horror film where the horror comes last. The moral dilemma of what Clive Nicoli (Adrien Brody) and Elsa Kast (Sarah Polley) are doing ...

In a way, myth became reality when the ancient Greek concept of a chimera — a monstrous mash-up of different animals — became standard terminology in biology, describing genetic hybrids. The ...

Matt Goldberg has been an editor with Collider since 2007. As the site's Chief Film Critic, he has authored hundreds of reviews and covered major film festivals including the Toronto International ...

Mad science meets motherhood in "Splice," a slice of pulp storytelling in which Dr. Frankenstein is replaced by a pair of lovers too hip for lab coats. By THR Staff More Sundance reviews PARK CITY — ...