Prolonged sperm storage may reduce motility and vitality through oxidative stress and DNA damage, thereby affecting fertility ...

The study focused on rare DNA damage-repair (DDR) disorders, including Ataxia-Telangiectasia (A-T) and Bloom syndrome. These ...

Disproportionate risks for multiple myeloma, a type of blood cancer, occur with environmental and occupational exposure.

A protein best known for driving cancer growth also helps damaged tumor cells survive by repairing their DNA, according to a ...

Reactive oxygen species (ROS) from mitochondria are key drivers of genetic chaos in cancer by causing the collapse of micronuclear envelopes, a process that fuels the chromosomal instability (CIN) ...

A new study led by NYU Langone Health researchers has found that cancer cells are better able to resist treatments when they ...

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury. This review sheds light on the ...