This confocal microscope image shows midbrain neurons (red) co-expressing the mu-opioid receptor (Oprm1, white) and cannabinoid receptor 1 (Cnr1, green). The interaction of these two reward pathways ...
Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid receptors. What they didn't know—until now—was exactly what happens next. A ...