Researchers suggest targeting mTOR activity in aggressive cancers by blocking cholesterol sensing may represent a promising ...

Transmission electron microscopic image of an isolate from the first U.S. case of COVID-19, formerly known as 2019-nCoV. The spherical viral particles, colorized blue, contain cross-section through ...

While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for ...

Lysosomes are thought of as cellular organelles that play an important role in recycling proteins and maintaning cells by breaking down stuff that isn’t needed. But new research has found that ...

(A) Gal3-GFP-expressing Jurkat cells were treated with 4 μmol/L of NeoL for 1 h, and immunolabeled for STING (red). Two cells in the same field under NeoL treatment were imaged by confocal microscopy.

Scientists have uncovered a surprising partnership between mitochondria and lysosomes that reshapes our understanding of cell biology. Instead of relying solely on the cytosol for protons, lysosomes ...

The mechanism by which cells detect leaky lysosomes has been revealed, laying the groundwork for new treatments for diseases where lysosomal damage plays a central role. When the cell’s recycling ...