The assignee for this patent application is Medarex, L.L.C. Reporters obtained the following quote from the background information supplied by the inventors: “The large-scale, economic purification of ...

With new upstream bioprocessing technologies continuing to increase yield and product quantities, the pressure for process improvement has fallen firmly on the downstream purification stage. The ...

Ion exchange chromatography (IEX) is a versatile and widely used technique for separating biomolecules based on charge. It plays a critical role in protein purification in research and ...

Ion exchange separates components in a sample depending on their relative ionic strengths and interaction with the stationary phase. The stationary phase is a charged substance that selectively ...

When ion-exchange chromatography and mass spectrometry are coupled using electrochemical ion suppression, it allows for the selective and specific analysis of highly polar and ionic compounds. The ...